Open Knee: Open Source Modeling & Simulation to Enable Scientific Discovery and Clinical Care in Knee Biomechanics

The goal of the Open Knee project is to provide a freely available and open source finite element representation of the knee for predictive simulations of joint loading and its effects on the underlying tissue structures. The model, as presented in here, is a work in progress and distributed as is. It can be utilized for learning finite element analysis in joint biomechanics; to understand the mechanical function of the knee and its components; and pending verification and validation, for scientific research on the mechanics of the joint as a whole and of its individual tissue structures. The users are expected to consult on the 'Known Limitations' section to evaluate the capacity of the model for their use. This document describes how to use the model, i.e. conduct simulations with different loading conditions, and also details the underlying development efforts for those interested in customizing the model for their needs or to help increase confidence in model predictions by addressing known limitations, and performing sensitivity and validation simulations. For bleeding edge information on Open Knee, please refer to https://simtk.org/home/openknee.